Comparing the efficacy of permethrin and dimethicone in treatment of head lice infestation

Comparing the efficacy of permethrin 1% and dimethicone 4% in treatment of primary school girls with head lice infestation: a clinical trials

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171117037512N2

Enrollment

Registered

2018-02-22

Start date

2018-02-20

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head lice. Pediculosis due to Pediculus humanus capitis

Interventions

Intervention 1: Group 1 intervention: In the treatment group with dimethicone, lotion dimethicone 4% will be pealed around the hairs from the root to the top. It should be normally dried and stayed a

Eligibility

Sex/Gender

Female

Age

6 Years to 13 Years

Inclusion criteria

Inclusion criteria: Female gender age between 6 and 13 years being infected with head lice having normal general condition

Exclusion criteria

Exclusion criteria: History of any sensitivity to anti-pediculosis drugs Dermatologic disorders Secondary bacterial infection Scalp burning Asthma Using hair care products Using anti-pediculosis drugs during the last seven days

Design outcomes

Primary

Measure	Time frame
Cure rate in each group as no evidence of any adult lice, nymph or egg. Timepoint: Before intervention, days 7, 14 and 21. Method of measurement: Examination of samples by an expert medical entomologist.	—

Secondary

Measure	Time frame
Dermal and periorbital allergic reactions. Timepoint: Before intervention, days 7, 14 and 21. Method of measurement: Sample examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahmood Moosazadeh

Sari University of Medical Sciences

mmoosazadeh1351@gmail.com+98 11 3325 7230

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026