Fluoxetine Therapeutic Effects With Duloxetine in patients with IBS with constipation

Comparison of Fluoxetine Therapeutic Effects With Duloxetine in patients with IBS with constipation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171115037478N1

Enrollment

120

Registered

2018-02-07

Start date

2017-11-21

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome is a type of constipation. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group1: The first group of dicyclomin tablets is given every 8 hours with fluoxetine 20 mg daily for 2 months. Intervention 2: Intervention group 2: The second group of di

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: new cases of irritable bowel syndrome aged 18-45 constipation predominant symptoms consistent with the criteria Rome2 criteria

Exclusion criteria

Exclusion criteria: patients with night diarrhea patients with weight loss patients with history of GI bleeding patients that use alcohol, drugs and opiums. patients with psychological diseases patients with CNS disorders patients with kidney or liver failure cardica patients

Design outcomes

Primary

Measure	Time frame
Severity of illness in irritable bowel syndrome, constipation type. Timepoint: At the beginning of the study and two months later. Method of measurement: IBS-SSS(IBS-(Severity scoring system).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehnam sajedi

Zanjan University of Medical Sciences

Behnamsajedi1365@zums.ac.ir+98 24 3377 0801

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026