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Effect of inhaler salbutamol versus placebo on treatment of neonatal transient tachypnea

Effect of inhaler salbutamol versus placebo on treatment of neonatal transient tachypnea: a double blind randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201711139014N201
Enrollment
52
Registered
2017-11-15
Start date
2017-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal transient tachypnea. Transient tachypnoea of newborn

Interventions

Intervention 1: Intervention group: 0.1 ml/kg salbutamol and 2 ml normal saline 0.9% plus 5 to 6 l/min oxygen for 20 min will be nebulized. Intervention 2: Control group: 2 ml normal saline 0.9% plus
Treatment - Drugs
Placebo
Intervention group: 0.1 ml/kg salbutamol and 2 ml normal saline 0.9% plus 5 to 6 l/min oxygen for 20 min will be nebulized.
Control group: 2 ml normal saline 0.9% plus 5 to 6 l/min oxygen for 20 min will be nebulized.

Sponsors

Vice-chancellor for Research and Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Months to 11 Months

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 34 to 47 weeks; neonatal transient tachypnea. Exclusion criteria: Pneumothorax; maternal addiction; respiratory distress syndrome; meconium aspiration; pneumonia; sepsis; congenital heart disease; pulmonary hypertension.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Number of breathing. Timepoint: Before and 0.5, 1 and 4 hours after treatment. Method of measurement: By physical examination.;TTN clinical score. Timepoint: Before and 0.5, 1 and 4 hours after treatment. Method of measurement: By physical examination.;Arterial oxygen saturation. Timepoint: Before and 4 hours after treatment. Method of measurement: By checking arterial blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Nishtman Sadeghi

Fatemieh Hospital

nishti_sadeghi@yahoo.com+98 81 3828 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026