Comparison of the Effectiveness of Desmopressin-Oxybutynin with Fluvoxamine in Treatment of Nocturnal Enuresis in Children

Comparison of the Effectiveness of Desmopressin-Oxybutynin with Fluvoxamine in Treatment of Nocturnal Enuresis in Children referring to Nephrology Clinic

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171112037417N1

Enrollment

Registered

2018-05-20

Start date

2018-04-25

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nocturnal Enuresis. Enuresis not due to a substance or known physiological condition

Interventions

Intervention 1: Intervention group: Patients are prescribed 25 milligram of Fluvoxamine nightly for one month. Intervention 2: Control group: Patients will be given Oxybutynin drug with dose of 0.1 mi

Eligibility

Sex/Gender

All

Age

8 Years to No maximum

Inclusion criteria

Inclusion criteria: Older than eight years old patients with Nocturnal Enuresis resistant to behavioral therapy & first-line medication therapy

Exclusion criteria

Exclusion criteria: Patients with Major Depression Disorder,Anxiety,etc

Design outcomes

Primary

Measure	Time frame
Rate of control and improvement of nocturnal enuresis after use of Fluvoxamine. Timepoint: A month after use of Fluvoxamine. Method of measurement: Medical response is divided to 3 levels as following: 1-no response 2- relative response as reduction of nocturnal enuresis to less than 2 times in a month and 3- complete improvement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnoosh Azarfar

Mashhad University of Medical Sciences

azarfara@mums.ac.ir+98 51 3726 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026