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Effect of topical Cedar on Acne

Evaluation the effectiveness of Ziziphus spina-christi topical solution plus clindamycin 1% compared with Clindamycin1% plus placebo in mild to moderate acne

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171112037409N1
Enrollment
110
Registered
2018-05-04
Start date
2018-05-04
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group: The topical solution of clindamycin (1%), with topical cedar solution, is applied 2 times a day for 6 weeks on the face. Intervention 2: Control group: The topical

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Subjects in age of 15 to 45 years old Chief complaint: mild to moderate Acne vulgaris subject willingness of herbal topical medicines use

Exclusion criteria

Exclusion criteria: pregnancy lactation History of polycyctic ovary use of acnegenic medications such as corticosteroid, hurmonal or anti-psychotic medications mechanical acne and gram-negative folliculitis History of dermal allergy

Design outcomes

Primary

MeasureTime frame
Total lesion count. Timepoint: at the beginning of the study, 2nd, 6th and 8th weeks. Method of measurement: counting the comedones, papules and pustules.;Severity of Acne. Timepoint: at the beginning of the study, 2nd, 6th and 8th weeks. Method of measurement: Acne Severity Index.

Secondary

MeasureTime frame
Adverse effects including redness, burning and itching. Timepoint: 2nd, 6th and 8th weeks of study. Method of measurement: observation and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRasoul Shakiba

Iran University of Medical Sciences

rasoul.shakiba@yahoo.com+98 215569321

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026