Knee Osteoarthritis. Bilateral primary osteoarthritis of knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Negative Ballottement test Negative Fluid wave test Age from 38 years old to 70 years old of both sex Diagnosed as knee osteoarthritis according to clinical criteria of American College of Rheumatology Having grade 2 and 3 based on Kellgern and Lawrence Grading Scale Complain of pain, crepitation and knee joint stiffness that lasted at least three months before study
Exclusion criteria
Exclusion criteria: Foot deformity Sever genu valgum Any infection involving the knee skin Any intra or peri articular injection during the three last months History of rheumatic or inflammatory disease involving the knee joints Prior total knee arthtoplasty Poorly controlled DM with HbA1c more than 7.5% BMI more than 42 History of knee trauma or fracture during the three last months History of acute lumbosacral radiculopathy or peripheral neuropathy History of cancer Bleeding disorders Pregnancy Severe genu varum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before injection, 4 and 8 weeks after injection. Method of measurement: Visual Analog Scale (VAS).;Function. Timepoint: Befor injection and 2 and 4 weeks after injection. Method of measurement: The WOMAC consists of 24 items divided into 3 sub scales : Pain (5 items): during walking, using stairs, in bed, sitting or lying, and standing.Stiffness (2 items): after first waking and later in the day.Physical Function (17 items): stair use, rising from sitting, standing, bending, walking, getting in / out of a car, shopping, putting on / taking off socks, rising from bed, lying in bed, getting in / out of bath, sitting, getting on / off toilet, heavy household duties, light household duties. | — |
Countries
Iran (Islamic Republic of)
Contacts
Shiraz University of Medical Sciences