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Comparison of the effect of Ibuprofen, Naufafen, Mefenamic acid and Celecoxib on the improvement of dental pain in the stage before the endodontic emergencies

A comparative study of analgesic effects of Ibuprofen, Novafen, Mefenamic acid and Celecoxib in relieving pain of symptomatic pulpitis before emergency endodontic intervention

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171109037332N1
Enrollment
120
Registered
2018-01-06
Start date
2017-12-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

symptomatic pulpitis. pulpitis

Interventions

Intervention 1: First Intervention group: Ibuprofen 400 once. Intervention 2: Second intervention group: Novafer once, containing 325 mg of acetaminophen, 40 mg of caffeine and 200 mg of ibuprofen. In
First Intervention group: Ibuprofen 400 once
Second intervention group: Novafer once, containing 325 mg of acetaminophen, 40 mg of caffeine and 200 mg of ibuprofen.
Third intervention group: Mefenamic acid 250 once
Fourth intervention group: Celecoxib 200 once

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The patient has an irreversible acute pulpitis, diagnosed by a dentist; Lack of medical problem (20) (such as history of stroke or heart failure, heart failure, blood pressure, asthma, nasal polyps, liver or kidney disease, gastric ulcer, systemic lupus, blood clotting problems, etc.); Access to the patient; Patients without oral disease and history of corticosteroid susceptibility are nonsteroidal inflammation; The teeth should be permanent with closed apex; Failure to quickly deal with endodontic emergencies; Patient satisfaction and compliance form completion

Exclusion criteria

Exclusion criteria: Patients who have received a home for up to 6 hours before; Patients who for any reason prohibit the use of the drugs studied.

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: Measure the severity of pain at the beginning of the study (before the intervention) and 1 hour after taking the drug. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoma kamyabi

Kerman University of Medical Sciences

h.kamyabi1244@gmail.com+98 34 3211 9028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026