overweight and obesity.
Conditions
Interventions
Intervention 1: Intervention group: Subjects in intervention group will receive 500 milligram curcumin supplements (1 per day) for 10 week. The curcumin supplements will provide from Karen pharmaceuti
Treatment - Other
Intervention group: Subjects in intervention group will receive 500 milligram curcumin supplements (1 per day) for 10 week. The curcumin supplements will provide from Karen pharmaceutical and dietary
Control group: Subjects in control group will receive placebo (1 per day) for 10 week. The placebo will provide from Karen pharmaceutical and dietary supplements company, Tehran, Iran. The placebo wil
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
13 Years to 18 Years
Inclusion criteria
Inclusion criteria: overweight or obese girls (BMI percentile >=85 for age), age 13-18 years old, having menstural cycles far at least 6 months
Exclusion criteria
Exclusion criteria: not consuming any drugs including drugs that could affect on lipid and carbohydrate metabolism such as statins and metformin, hormone therapy drugs, multivitamin-minerals, corticosteroids and nonsteroidal anti-inflammatory drugs no history of chronic diseases including diabetes, hypo- and hyperthyroidism, liver or renal diseases, cardiovascular diseases, polycystic ovary syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At the beginning of study- week 10. Method of measurement: Seca scale.;Height. Timepoint: At the beginning of study- week 10. Method of measurement: Strip meter.;Waist circumference. Timepoint: At the beginning of study- week 10. Method of measurement: Strip meter.;Hip circumference. Timepoint: At the beginning of study- week 10. Method of measurement: Strip meter.;Body mass index. Timepoint: At the beginning of study- week 10. Method of measurement: formula.;Fasting blood sugar. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment.;Fasting Insulin. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment.;Homeostatic model assessment of insulin resistance. Timepoint: At the beginning of study- week 10. Method of measurement: formula. | — |
Secondary
| Measure | Time frame |
|---|---|
| C-reactive protein. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment.;Interleukin 6. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment.;Chemerin. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment.;Total Antioxidant Capacity. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment.;Malondialdehyde. Timepoint: At the beginning of study- week 10. Method of measurement: biochemical assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMozhgan Nourian
Esfahan University of Medical Sciences
Outcome results
None listed