intubation in trauma patient.
Conditions
Interventions
Intervention 1: Intervention group1:ketamine: ketamine 3 mg/kg IV infusion, administered once at the beginning of the intervention for induction during rapid sequence intubation. Intervention 2: Inter
Sponsors
Sanandaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All adult multiple trauma patients referring to Sanandaj Kowsar Hospital emergency department requiring rapid sequence tracheal intubation
Exclusion criteria
Exclusion criteria: allergy to drugs elevated intracerebral or intraocular pressure hypertention (Blood Pressure>= 160/110 mm Hg) severe endocrine disorders active lung disease tracheal stenosis obstructive sleep apnea airway obstruction laryngospasm pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death at emergency department or during admission at hospital. Timepoint: During emergency department and hospital admission. Method of measurement: Death declaration at his/her documents.;Duration of survival days during hospital admission. Timepoint: During emergency or hospital admission (from admission and intubation until death). Method of measurement: Number of survival days.;ICU-free days. Timepoint: During hospital admission from intubation to 28 days after admission (ICU-discharge point until 28 days after admission). Method of measurement: Number of ICU-free days.;Ventilator-free days. Timepoint: During hospital admission from intubation to 28 days after admission (the time of weaning from mechanical ventilation until 28 days after admission). Method of measurement: Number of ventilator-free days.;Vasopressor free days. Timepoint: During hospital admission from intubation to 28 days after admission (the time of stopping vasopressor infusion until 28 days after admission). Method of measurement: Number of vasopressor-free days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of transfused packed-RBCs. Timepoint: During the first 48 hours from admission. Method of measurement: Number of transfused packed-RBCs documented on patient file.;Sepsis incidence. Timepoint: During the first 28 days from admission. Method of measurement: Having 2 or more criteria form SIRS associated with an infection focus during the first 28 days from admission. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamed Sotoude
Sanandaj University of Medical Sciences
Outcome results
None listed