Ozone Therapy Effect on Multiple sclerosis

Comparison of Ozone Therapy and Routine Medical Treatment Effect on Disease Severity and Serum Level Changes of IL-33 in Patients with Multiple Sclerosis (MS)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171105037262N3

Enrollment

Registered

2018-03-14

Start date

2018-03-11

Completion date

Unknown

Last updated

2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Control group: Patients of this group will use interferon beta as a routine medical treatment for six months. EDSS will be assessed for each patient before and after treatment, and blo

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Having Multiple Sclerosis EDSS=0-4.5

Exclusion criteria

Exclusion criteria: Unwillingness to continue cooperation Any local or systemic inflammation

Design outcomes

Primary

Measure	Time frame
Disease severity. Timepoint: At the beginning of the intervention. Method of measurement: Questionnaire.;IL-33. Timepoint: At the beginning of the intervention. Method of measurement: ELISA.	—

Secondary

Measure	Time frame
Disease severity. Timepoint: At the end of the intervention. Method of measurement: EDSS.;IL-33. Timepoint: At the end of the intervention. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHassan Nikoueinejad

Bagheiat-allah University of Medical Sciences

hnikuinejad@yahoo.com+98 31 5554 2999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026