breast cancer. Malignant neoplasm of breast of unspecified site, female
Conditions
Interventions
Intervention 1: Intervention group: ketogenic diet? ketogenic diet contain (5-10% CHO,15-20% Protein, 70 -80% FAT based on 20% MCT from nutricia company). Intervention 2: Control group: Standard diet?
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with locally advanced and metastatic breast cancer (Stage III or IV) that will undergo chemotherapy for at least 3 months; Patients who accept ketogenic diet for 3 months; Between 18 -75 years old; BMI between 18.5 - 35.5; Karnofsky Performance Score more than 70%
Exclusion criteria
Exclusion criteria: Type I diabetes under Insulin therapy; Patients with liver, kidney or cardiac disease; Congenital metabolic disorders that impair Ketogenic diet such as Gluconeogenesis defect; Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete response rate. Timepoint: At the baseline and the end of the study. Method of measurement: clinical exam,lab test and imaging. | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin level. Timepoint: 0, 45, 90. Method of measurement: Eliza. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAdeleh Khodabakhshi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed