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The effect of Lycopene on Infertility

The effects of lycopene supplement on the Spermatogram and seminal total antioxidant capacity, Malondialdehyde, Glutathione Peroxidase and depression in infertile men

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171105037249N1
Enrollment
44
Registered
2018-01-20
Start date
2017-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertile. Oligospermia

Interventions

Intervention 1: The intervention group receives 25 milligrams of lycopene from 21 Cent. Company once a day and for three months. Intervention 2: Control group: The control group will take 25 mg (starc
Treatment - Drugs
Placebo
The intervention group receives 25 milligrams of lycopene from 21 Cent. Company once a day and for three months.
Control group: The control group will take 25 mg (starch) once a day for 3 months.

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Primary infertility based on WHO criteria All male infertile male patients with varicoceles other than those who meet exit criteria.

Exclusion criteria

Exclusion criteria: Testicular atrophy Hormonal disorders such as gonadotropins, testosterone and prolactin Ejaculation disorder Anatomical abnormalities such as hypospadias Urinary tract infection Drug in the last 6 months Azoospermia People who use anticoagulant drugs. Use of antioxidant supplements Being a smoker

Design outcomes

Primary

MeasureTime frame
Concentration, number and sperm movement. Timepoint: The beginning and the end of the study. Method of measurement: Spermogram.

Secondary

MeasureTime frame
Malondialdehyde, total antioxidant capacity, glutathione peroxidase. Timepoint: The beginning and the end of the study. Method of measurement: Biochemical.;Depression. Timepoint: The beginning and the end of the study. Method of measurement: DASS questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehran Nouri

Esfahan University of Medical Sciences

mehran_nouri@hlth.mui.ac.ir+98 31 3792 3175

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 18, 2026