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Comparison of the effect of two therapies methylphenidate and matrix-methylphenidate in methamphetamine abusers

Comparison of the effect of two therapies methylphenidate and matrix-methylphenidate on the severity of addiction, craving and treatment abstinence in methamphetamine abusers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171105037245N1
Enrollment
100
Registered
2017-12-09
Start date
2017-10-14
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methamphetamine Dependency. Other stimulant abuse with stimulant-induced psychotic disorder

Interventions

Intervention 1: The Matrix program, which consists of 22 sessions of cognitive and behavioral psychotherapy, will be performed weekly in two sessions of forty five minutes for 12 weeks. Intervention 2

Sponsors

Vice chancellor for research, Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 48 Years

Inclusion criteria

Inclusion criteria: being at the age of 20 to 48 years Methamphetamine dependence diagnoses accordingly Diagnostic and Statistical Manual of Mental Disorders fifth edition The dominant use of methamphetamine Seeking treatment for methamphetamine abuse

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the study Having severe psychotic disorders Suicide attempts within the past 12 months Major cardiovascular disorder Epilepsy Current alcohol or sedative physical dependence or cocaine dependence

Design outcomes

Primary

MeasureTime frame
Addiction Severity. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Addiction Severity Index.;Craving. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Desire for Drug Questionnaire (DDQ craving).

Secondary

MeasureTime frame
Mental health. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: General Health Questionnaire (GHQ).;Negative urine test for methamphetamine. Timepoint: Before intervention and 3, 6, 9 and 12 weeks after intervention. Method of measurement: Methamphetamine urine test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdollah Omidi

Kashan University of Medical Sciences

omidi-a@kums.ac.ir+98 31 5554 2999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 25, 2026