The effect of two types of aerobic exercises with different severity on serum SIRT1, some hepatocytes and angiogenic indices in women with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171104037225N1

Enrollment

Registered

2017-11-28

Start date

2017-07-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 Diabetes. Non insulin dependent diabete mellitus

Interventions

Control group: with no exercise Exercise groups: first group:5 sessions per week with moderate intensity for 8 weeks second group:3sessions per week with vigorous intensity for 8 weeks.

Lifestyle

Control group: with no exercise Exercise groups: first group:5 sessions per week with moderate intensity for 8 weeks second group:3sessions per week with vigorous intensity for 8 weeks

Eligibility

Sex/Gender

Female

Age

40 Years to 50 Years

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
SIRT1. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA kit(Bio Vision)- ng/ml.;Fibroblast Growth Factor21. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: By ELISA- pg/ml.;Fetuin A. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- ng/ml.;Nitric Oxide. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- µmol/l.;Vascular Endothelial Growth Factor. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- ng/ml.;Endostatin. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- ng/ml.	—

Measure

Time frame

SIRT1. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA kit(Bio Vision)- ng/ml.;Fibroblast Growth Factor21. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: By ELISA- pg/ml.;Fetuin A. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- ng/ml.;Nitric Oxide. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- µmol/l.;Vascular Endothelial Growth Factor. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- ng/ml.;Endostatin. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: ELISA- ng/ml.

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Secondary

Measure	Time frame
FBS. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: Autoanalyzer- mg/dl.;Glc 2HR. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;A1c. Timepoint: Before the intervention and after 8 weeks intervention. Method of measurement: %.;TG. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;Chol. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;HDL. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;LDL. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;Weight. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: Kg.	—

Measure

Time frame

FBS. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: Autoanalyzer- mg/dl.;Glc 2HR. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;A1c. Timepoint: Before the intervention and after 8 weeks intervention. Method of measurement: %.;TG. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;Chol. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;HDL. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;LDL. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: mg/dl.;Weight. Timepoint: Before the intervention (exercise) and after 8 weeks intervention. Method of measurement: Kg.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactExir Vizvari

Department of Physical education and sport science

vizvariexir@yahoo.com+98 17 3254 3255

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026