Effect of stress reduction on blood pressure

Comparison the effectiveness of group mindfulness-based stress reduction and group cognitive-behavioral stress management on biological markers and psychological symptoms in patients with essential hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017103137145N1

Enrollment

Registered

2017-11-14

Start date

2017-11-16

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential hypertension. Essential (primary) hypertension

Interventions

Intervention 1: The MBSR-based group intervention is based on the 8th session of Jon Kabat Zinn's approach, which lasts 1.5 hours each session. Intervention 2: Cognitive-behavioral stress management g

Lifestyle

Behavior

Treatment - Drugs

The MBSR-based group intervention is based on the 8th session of Jon Kabat Zinn's approach, which lasts 1.5 hours each session.

Cognitive-behavioral stress management group sessions are based on the Cognitive-Behavioral Stress Management Book (Anthony, Ironson, and Schneiderman, 2010). The duration of each session is 1.5 hours

The control group receives standard blood pressure treatment.

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Diagnosis of essential hypertension with uncontrolled hypertension despite the treatment according to a cardiologist evaluation; Age between 30 and 60 years; Consent to participate in the research based on the written informed consent form. Exclusion criteria: Secondary blood pressure; Having major depressive disorder; Generalized anxiety disorder; Panic disorder and Post traumatic stress disorder during 1 year ago; Receiving Mindfulness or cognitive-behavioral therapy by a psychologist or psychiatrist in the past.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: before and after of intervention. Method of measurement: Home Blood Pressure Monitoring (HBPM).;Stress oxidative. Timepoint: before and after of intervention. Method of measurement: proxidane and antioxidants balance (PAB).;Interleukin 6. Timepoint: before and after of intervention. Method of measurement: ELISA method using the Biovendor Germany IL-6 kit.;Anxiety. Timepoint: before and after of intervention. Method of measurement: Beck Anxiety Inventory.;Quality of life. Timepoint: before and after of intervention. Method of measurement: The World Health Organizetion Quality of Life Instrument – short form (WHOQOL-BREF).;Perceived stress. Timepoint: before and after of intervention. Method of measurement: perceived stress scale (PSS) cohen.	—

Measure

Time frame

Blood pressure. Timepoint: before and after of intervention. Method of measurement: Home Blood Pressure Monitoring (HBPM).;Stress oxidative. Timepoint: before and after of intervention. Method of measurement: proxidane and antioxidants balance (PAB).;Interleukin 6. Timepoint: before and after of intervention. Method of measurement: ELISA method using the Biovendor Germany IL-6 kit.;Anxiety. Timepoint: before and after of intervention. Method of measurement: Beck Anxiety Inventory.;Quality of life. Timepoint: before and after of intervention. Method of measurement: The World Health Organizetion Quality of Life Instrument – short form (WHOQOL-BREF).;Perceived stress. Timepoint: before and after of intervention. Method of measurement: perceived stress scale (PSS) cohen.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarshad Sheybani

Iran University of Medical Sciences

sheybani.f@tak.iums.ac.ir+98 21 4426 9039

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026