Effect of vitamin D supplementat on the level of serum vitamin D in preterm neonates

Comparing the effect of different doses of vitamin D supplement on the level of serum 25(OH) vitamin D and bone metabolism related factors in preterm neonates

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171030037093N4

Enrollment

100

Registered

2019-03-03

Start date

2018-07-25

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D deficiency in premature infants. Vitamin D deficiency

Interventions

Intervention 1: Intervention group: reciving 300 units of vitamin D through FMS supplement plus 100 units of A + D drop ( 400 unints per cc , Behsa) plus distilled water. Intervention 2: Interventi

Eligibility

Sex/Gender

All

Age

1 Days to 30 Days

Inclusion criteria

Inclusion criteria: Gestational age between 28 and 34 weeks The absence of major disorders and malformations The absence of systemic diseases, such as asphyxia and cholestasis

Exclusion criteria

Exclusion criteria: Supportive nutrition for more than 2 weeks Use of anticonvulsant and anti HIV drugs by the infant's mother Use of injectable vitamin D during the study Formula feeding Nephrocalcinosis in the infant

Design outcomes

Primary

Measure	Time frame
Serum level of 25 hydroxy vitamin D. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.;Serum level of calcium. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.;Serum level of Phosphorus. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.;Serum level of Alkaline phosphatase. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.	—

Measure

Time frame

Serum level of 25 hydroxy vitamin D. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.;Serum level of calcium. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.;Serum level of Phosphorus. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.;Serum level of Alkaline phosphatase. Timepoint: Beginning of study, Modified age 40 weeks after LMP. Method of measurement: Blood sample.

—

Secondary

Measure	Time frame
. Timepoint: . Method of measurement: .	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Choopani

Shahre-kord University of Medical Sciences

choopani.r@skums.ac.ir+98 38 3227 4004

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026