Comparison of the effect of two doses of tranexamic acid on hemodynamic changes in patients

Comparative study of the effect of two doses of tranexamic acid on intraoperative hemodynamic changes in patients undergoing adenotonsillectomy

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171030037093N33

Enrollment

Registered

2020-03-27

Start date

2020-04-03

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes. Abnormal blood-pressure reading, without diagnosis

Interventions

Intervention 1: Intervention group 1: First group receive 5mg / kg tranexamic acid from Caspian Pharmaceutical Company intravenously and slowly once during 10 minutes before surgery. Intervention 2: I

Eligibility

Sex/Gender

All

Age

5 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children aged 5 to 10 years are candidates for ASAI, ASAI adenotonsillectomy.

Exclusion criteria

Exclusion criteria: The patient has any underlying disease The patient has bleeding disorders Patient with coagulation disorders (PT, PTT, INR) The patient has metabolic disorders

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure. Timepoint: Before induction and during anesthesia every 15 minutes. Method of measurement: Mercury barometer.;Pulse rate. Timepoint: Before induction and during anesthesia every 15 minutes. Method of measurement: Pulse oximetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Shafa

Esfahan University of Medical Sciences

amir_shafa@med.mui.ac.ir+98 31 3445 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026