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Comparison of the effect of two compounds of Propofol-Remifentanil and Propofol-Hydralazine on volume of blood loss during dacryocystorhinostomy with general anesthesia

A comparative study on the effect of two compounds of Propofol-Remifentanil and Propofol-Hydralazine on volume of blood loss during dacryocystorhinostomy with general anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171030037093N30
Enrollment
80
Registered
2020-02-05
Start date
2020-02-20
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood loss during surgery.

Interventions

Intervention 1: First intervention group:In group A in a 50 cc syringe 40 cc propofol with 0.15 µg / kg remifentanil is prepared and eventually the infusion at a dose of 50-150 µg/kg/min will be start

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ASA I, II patients who are candidates for DCR surgery Age range 18 to 80 years No contraindication for Hydralazine, Remifentanil and Propofol Consent to participate in the study

Exclusion criteria

Exclusion criteria: Known allergies to medicines Having heart disease Having diabetes mellitus Obvious anemia Having hemoglobinopathy Having polycythemia Having liver disease Ischemic cerebrovascular disease Having respiratory failure Systemic hypertension Any complication that may alter the anesthesia program Occurrence of complications such as heart block, etc. that prohibit or restrict the continuation of the intervention

Design outcomes

Primary

MeasureTime frame
Bleeding volume. Timepoint: After intervention. Method of measurement: Suction.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Before and after intervention. Method of measurement: Non-invasive automatic barometer.;Heart rate. Timepoint: Before and after intervention. Method of measurement: Pulse Oximeter.;Length of staying in recovery. Timepoint: After intervention. Method of measurement: Modified Aldrete Score.;Surgeon satisfaction. Timepoint: After intervention. Method of measurement: likert scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Shetabi

Esfahan University of Medical Sciences

hamidrezashetabi@med.mui.ac.ir+98 31 3620 1992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026