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Comparison of efficacy of 4 anesthesia methods on changes in heart rate and blood pressure during laryngeal mask application

Evaluation of the effect of anesthesia induction with three medicinal compounds midazolam-nesdonal, propofol, and etomidate-propofol compared to thiopental alone on changes in heart rate and blood pressure during laryngeal mask application in eye surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171030037093N27
Enrollment
128
Registered
2020-01-07
Start date
2020-02-16
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adverse effect of general anesthetics. Adverse effect of unspecified general anesthetics

Interventions

Intervention 1: First Intervention group: The first group is given a combination of midazolam (0.04 mg / kg) - nesdonal (2.5 mg / kg). Intervention 2: Second Intervention Group: The second group is gi

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who have indications for general anesthesia surgery and LMA surgery Age over 18 years ASA score or American Society of Anesthesiologists score 1 or 2 Consent to participate in the study

Exclusion criteria

Exclusion criteria: If you have an underlying or systemic illness such as kidney failure, or uncontrolled heart failure, etc.

Design outcomes

Primary

MeasureTime frame
Heart rate. Timepoint: Before intubation and 1, 3 and 5 minutes after LMA application. Method of measurement: Pulse oximetry.;Blood pressure. Timepoint: Before intubation and 1, 3 and 5 minutes after LMA application. Method of measurement: Barometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamran Montazeri

Esfahan University of Medical Sciences

montazeri@med.mui.ac.ir+98 31 3620 1992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026