Comparison of three doses of tranexamic acid on reduction of cleft palate surgery bleeding

Comparative study of the effect of three doses of tranexamic acid on reduction of bleeding during cleft palate surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171030037093N26

Enrollment

Registered

2019-12-16

Start date

2020-03-30

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative bleeding in cleft palate surgery. blood loss

Interventions

Intervention 1: First intervention group: One group of patients undergoing cleft palate surgery after induction of anesthesia received 5 mg / kg tranexamic acid by slow intravenous injection. Interven

Eligibility

Sex/Gender

All

Age

No minimum to 3 Years

Inclusion criteria

Inclusion criteria: Age less than 3 years Has ASA class I, II No history of systemic disease Consent to participate in this study (by parents)

Exclusion criteria

Exclusion criteria: Prolonged surgery longer than 3 hours Incidence of surgical and anesthesia complications Hypersensitivity or other contraindications to tranexamic acid use A history of coagulation disorders (such as hemophilia) Prior surgery in the same area Children without parental consent or withholding of participation in the project

Design outcomes

Primary

Measure	Time frame
The volume of blood lost. Timepoint: During operation. Method of measurement: Check list.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Shafa

Esfahan University of Medical Sciences

amir_shafa@med.mui.ac.ir+98 31 3445 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026