The effect of fentanyl with ketamine on pain relief of methadone users

The comparison effect of intravenous fentanyl with low dose ketamine on pain relief in methadone user patients with limb fracture

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171030037093N25

Enrollment

100

Registered

2019-12-04

Start date

2019-09-11

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

limb fracture.

Interventions

Intervention 1: First intervention group: receives Fentanyl ampoules made by Aburaihan pharmaceutical Co. 1-2 mg/kg as single dose intravenously and slowly for 15 minutes. Intervention 2: Second inter

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Methadone users with limb fractures Ages 18 to 65 years Insensitivity to fentanyl and ketamine Maxillofacial failure No pregnancy Lack of severe head trauma and decreased level of consciousness No serious trauma to the chest and abdomen Instability in terms of vital signs No use of psychotropic drugs No history of neuropsychiatric disorders Consent to participate in this study.

Exclusion criteria

Exclusion criteria: Severe hypoxia

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: Before drug administration (at baseline), and at 15, 30 and 60 minutes after drug administration. Method of measurement: Based on Visual analog score from 0 to 10.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Farghani

Esfahan University of Medical Sciences

dr.forghani514@yahoo.com36690021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026