Effect of consumption of Gonal-F and Menogan on the fertility of infertile patients with Polycystic Ovary Syndrome

Comparison of pregnancy outcomes in infertile patients with polycystic ovarian syndrome receiving Menogon monotherapy alone and in patients receiving Gonal-F and Menogon for ovulation induction in women

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171030037093N10

Enrollment

100

Registered

2019-05-07

Start date

2019-06-02

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: For the first group, manogan injections containing 75 units of LH and 75 units of FSH were injected once a day and for 10-12 days. Intervention 2: Intervention grou

Eligibility

Sex/Gender

Female

Age

No minimum to 40 Years

Inclusion criteria

Inclusion criteria: Infection with polycystic ovary syndrome Age less than 40 years Induction of in vitro fertilization No response to treatment with clomiphene citrate in patients

Exclusion criteria

Exclusion criteria: Blocking both tubes as the cause of infertility Hypothalamic amenorrhea as the cause of infertility Early ovarian failure as the cause of infertility Infertility due to severe male or azoospermia Diabetes Problems with thyroid problems Kidney Disease Sensitization to letrozole and clomiphene

Design outcomes

Primary

Measure	Time frame
The number of ocits earned. Timepoint: 7 and 12 days after the intervention. Method of measurement: Vaginal ultrasound.;Endometrial thickness. Timepoint: 7 and 12 days after the intervention. Method of measurement: Measurement.;Number of cases of empty follicular syndrome. Timepoint: 7 and 12 days after the intervention. Method of measurement: Vaginal ultrasound.;The number of cases of ovarian hyperstimulation syndrome. Timepoint: 7 and 12 days after the intervention. Method of measurement: Based on the amount of free fluid in the abdomen with ultrasound.;Human Chorionic Gonadotropin. Timepoint: 16 days after the transfer of embryos. Method of measurement: Experiment.;Fetal heart rate. Timepoint: 6 weeks after fertilization. Method of measurement: FHR machine.	—

Measure

Time frame

The number of ocits earned. Timepoint: 7 and 12 days after the intervention. Method of measurement: Vaginal ultrasound.;Endometrial thickness. Timepoint: 7 and 12 days after the intervention. Method of measurement: Measurement.;Number of cases of empty follicular syndrome. Timepoint: 7 and 12 days after the intervention. Method of measurement: Vaginal ultrasound.;The number of cases of ovarian hyperstimulation syndrome. Timepoint: 7 and 12 days after the intervention. Method of measurement: Based on the amount of free fluid in the abdomen with ultrasound.;Human Chorionic Gonadotropin. Timepoint: 16 days after the transfer of embryos. Method of measurement: Experiment.;Fetal heart rate. Timepoint: 6 weeks after fertilization. Method of measurement: FHR machine.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Nemati

Shahre-kord University of Medical Sciences

Mertanem@yahoo.co.uk+98 38 3222 0478

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026