Effect of flaxseed oil supplementation on some inflammatory factors level in Patients with Coronary Artery Disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017102811288N13

Enrollment

Registered

2017-11-01

Start date

2017-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease. Atherosclerosis

Interventions

Intervention 1: Intervention Group|: 200 ml Of Milk Prepared With 1.5% Fat+ 2 % Flaxseed Oil (containing 2 g alpha linolenic acid)/day For 2 Months. Intervention 2: Control Group: 200 ml Of milk conta

Lifestyle

Intervention Group|: 200 ml Of Milk Prepared With 1.5% Fat+ 2 % Flaxseed Oil (containing 2 g alpha linolenic acid)/day For 2 Months

Control Group: 200 ml Of milk contained 1.5% fat/ Day For 2 Mounths

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Subjects with 30-65 years old; BMI equal 25-35 kg/m2, angiographically confirmed coronary artery disease with more than 50% stenosis of at least one of the major coronary vessels; ?Exclusion criteria: Heart failure (function class III and IV), Heart valve diseases; Diabetes dependent on insuline therapy or any other chronic disease; Consumption of any immunosuppressive drugs; Antioxidant and/or vitamin supplements; Fish oil or (n-3) fatty acid supplements; Weight loss drugs or weight loss surgery; Smoking and drug users; Pregnant and lactating women; Those with Lactase deficiency ( milk intolerance)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum Levels Of MMP-9. Timepoint: Pre And Post Intervention. Method of measurement: ELISA Kit.;Serum Levels Of MCP-1. Timepoint: Pre And Post Intervention. Method of measurement: ELISA Kit.	—

Secondary

Measure	Time frame
Energy And Macronutrient Levels. Timepoint: Pre And Post Intervention. Method of measurement: Food Record Questionnaire.;Physical Activity Level. Timepoint: Pre And Post Intervention. Method of measurement: International Physical Activity Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSevda Saleh- Ghadimi

Faculty Of Nutrition And Food Science, Tabriz University Of Medical Sciences

salehghadimisevda@gmail.com+98 41 3381 1902

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026