Chronic rhinosinusitis. Chronic sinusitis, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Symptoms of chronic sinusitis lasting more than 12 weeks Diagnosis of chronic rhinosinusitis based on EPOS (2012) criteria, requiring at least two major criteria or one major criterion and two minor criteria.
Exclusion criteria
Exclusion criteria: Use of topical corticosteroids within 15 days prior to enrollment Use of antibiotics within 15 days prior to enrollment Use of oral corticosteroids within 30 days prior to enrollment Multiple nasal polyps History of nasal or sinus surgery within the last 5 years Moderate to severe asthma or mild asthma with an acute exacerbation in the past 30 days Drug-induced rhinitis Known hypersensitivity to herbal medicines or excipients Symptoms and signs of bacterial sinusitis (fever =38.5°C, orbital complications, severe unilateral frontal pain, or dental pain) Acute fungal sinusitis Acute seasonal allergy Underlying Diseases like Cystic fibrosis, cardiac, renal, pulmonary, or hepatic failure, Neurological or psychiatric disorders, Substance or alcohol abuse, Malignancies or immunodeficiencies Pregnancy Breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of symptoms based on SNOT-22. Timepoint: Before intervention (day 0), and end of intervention (day 28). Method of measurement: SNOT-22 Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Day 7; day 28. Method of measurement: Ask the patient; The patient stated. | — |
Countries
Iran (Islamic Republic of)
Contacts
Mazandaran University of Medical Sciences