cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention 1: Intervention group: Sambucus Ebulus 5 % ointment two times a day a layer until the full lesion epithelialization or up to 4 weeks after last intervention. Intervention 2: Control group
Treatment - Drugs
Placebo
Intervention group: Sambucus Ebulus 5 % ointment two times a day a layer until the full lesion epithelialization or up to 4 weeks after last intervention
Control group: Placebo ointment two times a day a layer until the full lesion epithelialization or up to 4 weeks after last intervention
Sponsors
Vice chancellor for research of Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with lesions which lasts more than 14 days and definitely diagnosed cutaneous leishmaniasis by parasites seen in smears taken from skin lesions, and treating by the national standard treatment guidelines.
Exclusion criteria
Exclusion criteria: Pregnant women, patients with allergy to antimuan, patients taking more than three months have passed since the first appearance of skin lesions, patients in recent months any way be used to treat leishmaniasis, patients which their wound on the eyelids, ear, nose or are less than one centimeter is near the end of the lips and eyes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Longest diameter of ulceration area. Timepoint: 0,7,14,21,28 day& if not cured 4 week after last intervention. Method of measurement: Ruler.;Longest diameter of Induration area. Timepoint: 0,7,14,21,28 day& if not cured 4 week after last intervention. Method of measurement: Ruler.;Healing rate. Timepoint: 0,7,14,21,28 day& if not cured 4 week after last intervention. Method of measurement: Observation & calculation.;Treatment resualt. Timepoint: At the end of treatmen, and if lesion not full epithelialized 4 weeks after last intervention. Method of measurement: Observation & determination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect. Timepoint: During treatment. Method of measurement: Observation & interview. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactOmid Mozafari
Golestan University of Medical Sciences
Outcome results
None listed