Blood pressure control in both intravenous and inhalation anesthetics in sinus surgery

Comparison of blood pressure control in two general anesthetics technique of isoflurane and propofol in two anti hypertensive nitroglycerine-Labetalol or remifentanil in functional sinus endoscopic surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017102715108N3

Enrollment

Registered

2017-11-19

Start date

2017-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood pressure. Elevated blood-pressure reading, without diagnosis of hypertension

Interventions

Intervention 1: Intervention group 1: Patients undergoing inhaled anesthetic of isoflurane and receive nitroglycerine-Labetalol. Intervention 2: Intervention group 2: Patients undergoing inhaled anest

Treatment - Drugs

Intervention group 1: Patients undergoing inhaled anesthetic of isoflurane and receive nitroglycerine-Labetalol.

Intervention group 2: Patients undergoing inhaled anesthetic of isoflurane and receive remifentanil.

Intervention group 3: Patients undergoing vein anesthetic of propofol and receive nitroglycerine-Labetalol.

Intervention group 4: Patients undergoing vein anesthetic of propofol and receive remifentanil.

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients undergoing functional sinus endoscopic surgery that should have a systolic blood pressure of more than 100 and an arterial hypertension above 55. Exclusion criteria: Patients with history of hypertension; antihypertensive drugs; addicted patients; use of neurological drugs; patients with coagulation disorder and anticoagulants.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Amount of blood pressure. Timepoint: At the entrance to the operating room, after the induction, 15, 30, 45, 60, 75, 90, and 105 minutes during surgery. Method of measurement: In mmHg using a mercury barometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Reza Safaeian

Iran University of Medical Sciences

rezasafa@yahoo.com+98 21 4464 0531

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026