Comparison between two different diets in children and adolescents with cystic fibrosis

The comparison between high calorie, high fat diets with different glycemic indexes effect on some biomarkers related to diabetes and inflammatory factors and cytokines in children and adolecents with cystic fibrosis.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017102325267N5

Enrollment

Registered

2017-11-13

Start date

2017-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cystic fibrosis. cystic fibrosis

Interventions

Prevention

Intervention 1: Intervention group: following high fat, high calorie diet with low gycemic index for three months. Intervention 2: control group: following high fat, high calorie diet, with gycemic i

Intervention group: following high fat, high calorie diet with low gycemic index for three months

control group: following high fat, high calorie diet, with gycemic index higher than 55 for three months

Eligibility

Sex/Gender

All

Age

2 Years to 19 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children and adolescents aged 2-18; children and adolescents who affected disease is confirmed by genetic or sweat test; willingness to cooperate Exclusion criteria: unwilling to cooperate and continue; inability to pursue each types of the diet; urgent need of hospitalization during trial; urgent need of operation during trial

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Fasting blood glucose. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;HDL cholostrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically.;LDL cholestrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically.;Total cholestrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically.;HbA1c. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;INF gamma. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;IL17-A. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;IL-10. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;IL-6. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.	—

Measure

Time frame

Fasting blood glucose. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;HDL cholostrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically.;LDL cholestrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically.;Total cholestrol. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: measurement of variables blood level biochemically.;HbA1c. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;INF gamma. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;IL17-A. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;IL-10. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.;IL-6. Timepoint: pre intervention and 3 months after begining the diet. Method of measurement: ELISA Kit.

—

Secondary

Measure	Time frame
Height. Timepoint: begining of the trial and three months. Method of measurement: meter.;Weight. Timepoint: begining of the trial and three months. Method of measurement: Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Mahmoudi

Tehran University of Medical Sciences

mahmoodi_maryam@yahoo.com+98 21 8895 5698

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 28, 2026