Effect of zinc sulfate- hydroxyzine and hydroxyzine alone on malnutrition indices in hemodialysis patients

Comparison of the effect of zinc sulfate- hydroxyzine and hydroxyzine alone on malnutrition indices in hemodialysis patients: A clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017102136703N2

Enrollment

Registered

2017-11-08

Start date

2017-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease, hemodialysis. Chronic renal failure

Interventions

Intervention 1: Intervention group: one zinc sulfate capsule (220 mg) daily and one hydroxyzine tablet (25 mg) daily for 8 weeks. Intervention 2: Control group: one hydroxyzine tablet (25 mg) daily fo

Treatment - Drugs

Intervention group: one zinc sulfate capsule (220 mg) daily and one hydroxyzine tablet (25 mg) daily for 8 weeks

Control group: one hydroxyzine tablet (25 mg) daily for 8 weeks

Eligibility

Sex/Gender

All

Age

15 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: More than 15 years old; history of at least 6 months hemodialysis. Exclusion criteria: Zinc supplements usage; nephrotic syndrome; cancer

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
BMI. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Wt(kg)/Ht(m2).;Albumin. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Cholesterol. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Hemoglobine. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Cell Blood Count with sismex k1000.;Creatinin. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Arm durchmesser. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Meter.	—

Measure

Time frame

BMI. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Wt(kg)/Ht(m2).;Albumin. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Cholesterol. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Hemoglobine. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Cell Blood Count with sismex k1000.;Creatinin. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Arm durchmesser. Timepoint: Before the intervention and 4 and 8 weeks after intervention. Method of measurement: Meter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzita Roohi

Shahroud University of Medical Sciences

hossaini@shmu.ac.ir+98 23 3239 1796

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026