The effect of vitamin D and chemotherapy compared with chemotherapy in the treatment of chemotherapy after ovarian cancer surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017101833680N4

Enrollment

Registered

2017-10-27

Start date

2018-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ovarian cancer. Malignant neoplasms of female genital organs

Interventions

Intervention 1: The intervention group, a chemotherapy-like control group, is given 50000 unit of vitamin D orally 1 to 8 weeks. Intervention 2: The control group, the usual chemotherapy, includes th

Treatment - Drugs

The intervention group, a chemotherapy-like control group, is given 50000 unit of vitamin D orally 1 to 8 weeks.

The control group, the usual chemotherapy, includes the carboplatin and paclitaxel regimen every 3 weeks, once every 3 cycles with placebo will be done.

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age over 20 years; Patients with advanced stages of epithelial ovarian cancer, candidate for postoperative chemotherapy Exclusion criteria: history diseases such as Liver, kidney and etc.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Liver toxicity. Timepoint: After intervention. Method of measurement: Score.;Locopeni. Timepoint: After intervention. Method of measurement: Score.;Tumor examination. Timepoint: Before and after intervention. Method of measurement: Sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Setsre Kasaeian

Mashhad University of Medical Sciences

Setare.kasaeian@yahoo.com+98 51 3802 2608

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026