nicotine dependence. Mental and behavioural disorders due to use of tobacco
Conditions
Interventions
Intervention 1: Control Group: This group receives placebo for seven weeks. Intervention 2: Intervention group: Gemfibrozil 300 mg for twice daily mg for seven weeks.
Treatment - Drugs
Control Group: This group receives placebo for seven weeks
Intervention group: Gemfibrozil 300 mg for twice daily mg for seven weeks
Sponsors
Vice chancellor for research of Kashan University of Medical Sciences and Health Services
Eligibility
Sex/Gender
All
Age
19 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Having an age of 19–65 years; nicotine dependence based on DSM 5; lack of history of psychotic disorders; having negative results in opioid and amphetamines test; lacking diagnosis of chronic disease such as debate, blood pressure , cancer and etc; Not be pregnant. Exclusion criteria: Unwillingness to continue participating in the study; being pregnancy during study; uses drugs with contraindication or Interference with Gemfibrozil such as Anticoagulants, statins, other fibrates and niacin.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Smoking cessation. Timepoint: Before intervention; 1,2,3,4,5,6,7,8,11,14,19 after beginning of intervention. Method of measurement: Expiratory CO2 concentration.;Nicotine dependence. Timepoint: Before intervention; 1,2,3,4,5,6,7,8,11,14,19 after beginning of intervention. Method of measurement: fagestrom nicotine dependence scale.;Nicotine Withdrawal. Timepoint: Before intervention; 1,2,3,4,5,6,7,8,11,14,19 after beginning of intervention. Method of measurement: Minnesota Nicotine Withdrawal Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaohamadreza Davoudi
Kashan University of Medical Sciences and Health Services
Outcome results
None listed