moderate to severe chronic periodontitis. Chronic periodontitis
Conditions
Interventions
Intervention 1: Intervention group: Non-surgical periodontal treatment and daily administration of resveratrol 480 mg capsule, produced by Herbafit company (Germany) for 4 weeks. Intervention 2: Contr
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: age between 30 to 60 years old chronic moderate to severe periodontitis
Exclusion criteria
Exclusion criteria: Pregnancy Breast feeding Traveling for more than 2 weeks Smoking Using immunosuppressive medications Using NSAIDs Using anti hypertension drugs or Medications that slow blood clotting such as warfarin Using insulin Affecting by uterine cancer, breast cancer or ovarian cancer or being under cancer treatment Advanced kidney and liver problems Allergy to black grapes or blueberry Periodontal treatment history during the past 6 months Considerable changes in diet over the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth. Timepoint: Beggining of study and 1 month later. Method of measurement: Williams probe.;Clinical Attachment Loss. Timepoint: Beggining of study and 1 month later. Method of measurement: Using the Williams probe.;Plaque Index. Timepoint: Beggining of study and 1 month later. Method of measurement: By colloring with disclosing pills and calculating the percentage of whole mouth.;Bleeding Index. Timepoint: Beggining of study and 1 month later. Method of measurement: Checking Bleeding on probing in the mouth and measuring its percentage.;The level of IL-8 in saliva. Timepoint: Beggining of study and 1 month later. Method of measurement: Eliza kit.;The level of IL-1ß in saliva. Timepoint: Beggining of study and 1 month later. Method of measurement: Eliza kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShabnam Nikniaz
Yazd University of Medical Sciences
Outcome results
None listed