Effects of adjunctive use of 2% atorvastatin dentifrice plus vitamin C in treatment of teeth supporting tissues disease.

Effects of adjunctive use of 2% atorvastatin dentifrice plus vitamin C in treatment of chronic periodontitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171015036782N5

Enrollment

Registered

2018-09-26

Start date

2018-09-23

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate to severe chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Control group: non-surgical periodontal treatment and daily administeration of 0.2% fluoride toothpaste for 4 weeks. Intervention 2: Intervention group: non-surgical periodontal trea

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: age between 30 to 60 years old chronic moderate to severe periodontitis

Exclusion criteria

Exclusion criteria: Pregnancy Breast feeding Smoking Using immunosuppressive medications Using NSAIDs Using antibiotics over the past 3 months Using a vitamin supplement or mouthwash Having an autoimmune disease Uncontrolled diabetes Hyperlipidemia disease Special diet

Design outcomes

Primary

Measure	Time frame
Probing depth. Timepoint: Beggining of study and 1 month later. Method of measurement: Williams probe.;Clinical Attachment Loss. Timepoint: Beggining of study and 1 month later. Method of measurement: Using the Williams probe.;Modified Gingival Index. Timepoint: Beggining of study and 1 month later. Method of measurement: by observation of the amount of inflammation in the mouth and then calibrate it.;Bleeding on probing. Timepoint: Beggining of study and 1 month later. Method of measurement: by observation of Bleeding on probing in the mouth and measuring its percentage.	—

Measure

Time frame

Probing depth. Timepoint: Beggining of study and 1 month later. Method of measurement: Williams probe.;Clinical Attachment Loss. Timepoint: Beggining of study and 1 month later. Method of measurement: Using the Williams probe.;Modified Gingival Index. Timepoint: Beggining of study and 1 month later. Method of measurement: by observation of the amount of inflammation in the mouth and then calibrate it.;Bleeding on probing. Timepoint: Beggining of study and 1 month later. Method of measurement: by observation of Bleeding on probing in the mouth and measuring its percentage.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhosein Vatandoust

Yazd University of Medical Sciences

amirhosein.vatandoust@yahoo.com+98 35 3830 1323

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026