effect of intravenous and intratechal dexmedetomidine on shivering

Comparison of efficacy of intravenous and intratechal dexmedetomidine on perioperative shivering after spinal anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171014036771N1

Enrollment

150

Registered

2019-01-16

Start date

2019-01-21

Completion date

Unknown

Last updated

2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shivering after spinal anesthesia.

Interventions

Intervention 1: Intervention group: intrathecal Dexmedetomidine group spinal anesthesia with 3ml (15mg) hyperbaric bupivacaine 0.5% (Marcaine spinal 0.5% AstraZe

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 18-70 years/old ASA class I-II lower abdominal and lower limb surgery spinal anesthesia for surgery Duration of surgery is 30-120 minutes.

Exclusion criteria

Exclusion criteria: Core body temperature higher than 37.5 ° C Pregnancy History of allergy to the drugs used in the study Contraindications for spinal anesthesia Patient with uncontrolled thyroid disease Parkinson's Disease disautonomy Raynaud syndrome Cardiopulmonary Disease History of alcohol consumption unstable coronary artery disease heart block (degree of II and III) congestive heart failure severe mitral stenosis vasodilator drugs consumption Surgeries requiring washing with excess fluid (eg TURP).

Design outcomes

Primary

Measure	Time frame
Shivering. Timepoint: During surgery every 5 minutes and during recovery every 15 minutes. Method of measurement: shivering Usta and Gozdemir scale.	—

Secondary

Measure	Time frame
Core temperature. Timepoint: Every 15 minutes from the start of surgery to the end of recovery. Method of measurement: digital tympanic thermometer.;Heart rate. Timepoint: The first 15 minutes of starting surgery every 5 minutes and then until the end of recovery every 15 minutes. Method of measurement: Digital Cardiac Monitoring.;Systolic blood pressure. Timepoint: The first 15 minutes of starting surgery every 5 minutes and then until the end of recovery every 15 minutes. Method of measurement: Digital Cardiac Monitoring.;Diastolic blood pressure. Timepoint: The first 15 minutes of starting surgery every 5 minutes and then until the end of recovery every 15 minutes. Method of measurement: Digital Cardiac Monitoring.	—

Measure

Time frame

Core temperature. Timepoint: Every 15 minutes from the start of surgery to the end of recovery. Method of measurement: digital tympanic thermometer.;Heart rate. Timepoint: The first 15 minutes of starting surgery every 5 minutes and then until the end of recovery every 15 minutes. Method of measurement: Digital Cardiac Monitoring.;Systolic blood pressure. Timepoint: The first 15 minutes of starting surgery every 5 minutes and then until the end of recovery every 15 minutes. Method of measurement: Digital Cardiac Monitoring.;Diastolic blood pressure. Timepoint: The first 15 minutes of starting surgery every 5 minutes and then until the end of recovery every 15 minutes. Method of measurement: Digital Cardiac Monitoring.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Pahlevani

Kashan University of Medical Sciences

pahlavani-h@kaums.ac.ir+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026