Effect of zinc sulfate on sleep quality in hemodialysis patients

Comparison of the effect of zinc sulfate and placebo on sleep quality in hemodialysis patients: A clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017101036703N1

Enrollment

100

Registered

2017-11-17

Start date

2017-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

zinc deficiency. Dietary zinc deficiency

Interventions

Intervention 1: Intervention group: one Zinc sulfate capsule (220 mg) daily for one month and then two zinc sulfate capsule (440 mg) daily for second months. Intervention 2: Control group: one placebo

Treatment - Drugs

Placebo

Control group: one placebo capsule daily for one month and then two placebo capsule daily for second months

Intervention group: one Zinc sulfate capsule (220 mg) daily for one month and then two zinc sulfate capsule (440 mg) daily for second months.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: History of at least 6 months hemodialysis for three time in week; sleep quality score lower than 5. Exclusion criteria: Zinc supplements usage; immunosuppressive drugs usage; history of psychiatric, cardiopolmonary and infectious disease in three past months.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sleep quality. Timepoint: Before the intervention and 8 weeks after intervention. Method of measurement: Pittsburgh Sleep Quality Index questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Hosseini

Shahroud University of Medical Sciences

hosseini@shmu.ac.ir+98 23 3239 1796

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026