acne.
Conditions
Interventions
interventional group(topical niosomal 4% erythromycin suspension) BD ,until 3 months
control group( topical erythromycin 4% and zinc acetate 1.2% ) BD ,until 3 months.
Treatment - Drugs
interventional group(topical niosomal 4% erythromycin suspension) BD ,until 3 months
control group( topical erythromycin 4% and zinc acetate 1.2% ) BD ,until 3 months
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
12 Years to 35 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria were those with mild to moderate acne vulgaris and 12-35 years old. The exclusion criteria were as follows: pregnant or lactating women, people with known hypersensitivity to erythromycin and zinc acetate, treatment with oral isotretinoin within last 6 months, oral estrogen compounds within last 3 months, topical retinoid compounds and antibiotics within last 1 month, patients with hirsutism, androgenetic alopecia and polycystic ovary syndrome.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of inflammatory,non-inflammatory acne lesions,quality of life before and after the treatment. Timepoint: 2,4,8,12 weeks. Method of measurement: counting of the inflammatory,noninflammatory and total acne lesions,assessment of quality of life by Cardiff acne disability index ( CADI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects(erythema,burning and itching sensation,peeling). Timepoint: 2,4,8,12 weeks. Method of measurement: by question of patients and physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactmahin aflatoonian
Kerman University of Medical Sciences, Iran
Outcome results
None listed