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Impact of Coffeine on wheezing of children

The Effect of Coffeine on Wheezing of 3- 36 Month Children

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171009036678N2
Enrollment
136
Registered
2019-07-18
Start date
2014-12-27
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Wheezing. Condition 2: cough. Wheezing Cough

Interventions

Intervention 1: Intervention group: 10 mg/ kg Oral Coffein in 2 equal divided dosage at the morning and evening in combination with Salbutamol. Intervention 2: Control group: Salbutamol spray as rou

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Months to 3 Years

Inclusion criteria

Inclusion criteria: Wheezing due to bronchiolitis Wheezing due to viral disease of lower respiratory tract Wheezing due to increased airway sensitivity Wheezing due to mild permanent asthma The ability to eat drugs Written consent of parents for participation of children in the research

Exclusion criteria

Exclusion criteria: Dyspnea Pneumonia Seizure Wheezing due to cystic fibrosis Wheezing due to foreign body History of prematurity Taking antibiotic Taking anti-acid

Design outcomes

Primary

MeasureTime frame
Wheezing. Timepoint: Before intervention and 48 hour, 1 week and 2 week after the beginning of the research intervention. Method of measurement: Physical examination by pediatrician.;Daily cough. Timepoint: Before intervention and 48 hour, 1 week and 2 week after the beginning of the research intervention. Method of measurement: History taking by pediatrician.;Night cough. Timepoint: Before intervention and 48 hour, 1 week and 2 week after the beginning of the research intervention. Method of measurement: History taking by pediatrician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Marjan Esfahani

Yasouj University of Medical Sciences

beheshtihospital@yasooj.ir+98 74 3322 4721

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026