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Evaluation & safety of lactated ringer’s solution on prevention of acute pancreatitis

Evaluation of efficacy & safety of aggressive hydration therapy with ringer’s lactated solution on pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP) in patient candidate for ERCP

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171009036664N1
Enrollment
164
Registered
2018-01-11
Start date
2017-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pancreatitis. Acute pancreatitis

Interventions

Intervention 1: Intervention group: serum lactate ringer with 20 cc/Kg was administered bolus and then with a dose of 3 cc/Kg to 8 hours after ERCP. Intervention 2: Control group: Serum lactate ringe
Prevention
Intervention group: serum lactate ringer with 20 cc/Kg was administered bolus and then with a dose of 3 cc/Kg to 8 hours after ERCP
Control group: Serum lactate ringer is given at a dose of 1.5 cc / kg up to 8 hours after ERCP.

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 70 Years

Inclusion criteria

Inclusion criteria: Indication for endoscopic retrograde cholangiopancreaticography (ERCP); Consent of enrollment in the study

Exclusion criteria

Exclusion criteria: Acute cholangitis; Sepsis; Pregnancy; Age above 70 years; Chronic pancreatitis; Acute pancreatitis due to billiary stone; evidence of fluid overload; Peripheral edema; Pulmonary edema; Electrolyte disturbance for example Na over 150 or below 130; Cirrhosis Renal failure History of endoscopic retrograde cholangiopancreaticography performation with sphinctrotomy

Design outcomes

Secondary

MeasureTime frame
Complications of ERCP. Timepoint: 6, 12 and 24 hours after endoscopicretrograde cholangiopancreatography procedure. Method of measurement: Clinical examination.

Primary

MeasureTime frame
Post endoscopicretrograde cholangiopancreatography pancreatitis. Timepoint: 6, 12 and 24 hours after endoscopicretrograde cholangiopancreatography procedure. Method of measurement: Clinical examination (abdominal pain) & laboratory testing(amylase, and/or lipase levels to =3 times the upper limit of normal).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNafise Mohmmadpanahi

Qazvin University of Medical Sciences

dr.n.panahi@gmai.com+98 28 3376 0620

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026