The effect of two resistance training models on hormones, muscle performance, and delayed onset muscle soreness in untrained men

The effect of two resistance training models, rest-pause and superset, on hormones related to hypertrophy and muscle metabolism, delayed onset muscle soreness, and collagen breakdown in untrained men

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171009036662N1

Enrollment

Registered

2026-01-07

Start date

2026-01-21

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of two resistance training models, rest-pause and superset, on hormones related to hypertrophy and muscle metabolism, delayed onset muscle soreness, and collagen breakdown in untrained men.

Interventions

Intervention 1: Intervention group: The resistance training program will be performed using a superset method at an intensity of 75% of 1-RM. Participants will perform the training session with 10 min

Eligibility

Sex/Gender

Male

Age

20 Years to 27 Years

Inclusion criteria

Inclusion criteria: man not trained in 4-6 months men aged 20 to 27 years, inclusive

Exclusion criteria

Exclusion criteria: skeletal, muscular, cardiovascular, or hormonal disorders women and trained individuals smokers

Design outcomes

Primary

Measure	Time frame
Growth Hormone (GH). Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Insulin-like Growth Factor (IGF-1). Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Cortisol. Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Testosterone. Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Lactate. Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Creatine Kinase (CK). Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Lactate Dehydrogenase (LDH). Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Hydroxy lysine. Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Hydroxy proline. Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Rating of Perceived Exertion(RPE). Timepoint:	—

Measure

Time frame

Growth Hormone (GH). Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Insulin-like Growth Factor (IGF-1). Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Cortisol. Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Testosterone. Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Lactate. Timepoint: Before the exercise and immediately after the exercise. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Creatine Kinase (CK). Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Lactate Dehydrogenase (LDH). Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Hydroxy lysine. Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Hydroxy proline. Timepoint: Before the activity and 24, 48, and 72 hours after completing the activity. Method of measurement: Blood samples from the brachial vein in a seated position, following standard hygienic procedures.;Rating of Perceived Exertion(RPE). Timepoint:

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPegah Movahedpour

The University of Guilan

pmovahedpour@webmail.ac.ir+98 13 3369 0274

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026