Effect of oral progesterone versus placebo on reducing preterm labor in women with a history of preterm labor

Effect of oral progesterone versus placebo on reducing preterm labor in women with a history of preterm labor: a double blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201710079014N192

Enrollment

214

Registered

2017-10-09

Start date

2017-01-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm labour. Preterm labour and delivery

Interventions

Intervention 1: Intervention group: Oral capsule medroxyprogesterone 100 mg twice a day until 36 weeks of pregnancy. Intervention 2: Control group: Oral capsule placebo twice a day until 36 weeks of p

Treatment - Drugs

Placebo

Intervention group: Oral capsule medroxyprogesterone 100 mg twice a day until 36 weeks of pregnancy.

Control group: Oral capsule placebo twice a day until 36 weeks of pregnancy.

Eligibility

Sex/Gender

Female

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 18 to 25 years; gestational age of 18 to 24 weeks; at least a history of one preterm labor between 20 to 36 weeks. Exclusion criteria: Bleeding in the first trimester; abnormal fetus; active liver disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Occurrence of preterm. Timepoint: Before 36 weeks of pregnancy. Method of measurement: By taking history.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Jamali

Fatemieh Hospital

m.jamali59@gmail.com+98 81 3828 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026