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Comparison of the effects of sensitizers on photodynamic therapy in Extracted teeth

Comparision Effect of Three Photosensitizers Include Methylene Blue, Toluidine Blue and Curcumin in Photodynamic Therapy Using Led Lamp (Light Emitting Diod) Against Enterococcus Faecalis in Extracted Human Teeth

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201710078146N26
Enrollment
60
Registered
2017-11-01
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enterococcus faecalis in Extracted teeth. Other and unspecified infectious diseases

Interventions

Intervention 1: Control group: Only the physiology serum is used in the channels. Intervention 2: Intervention group 1: washing with 5 ml 2.5% sodium hypochlorite for 2 minutes, up to 2 mm apex. Inter
Placebo
Treatment - Other
Control group: Only the physiology serum is used in the channels
Intervention group 1: washing with 5 ml 2.5% sodium hypochlorite for 2 minutes, up to 2 mm apex
Intervention group 2: Washing with 5 ml 2.5% sodium hypochlorite for 2 minutes. Then, an LED with methylene blue with a concentration of 100 µg for 120 seconds is used.
Intervention group 3: Washing with 5 ml 2.5% Hypochlorite for 2 minutes. Then, an LED with Toluidine blue with 100 micrograms for 120 seconds is used.
Intervention group 4: Washing with 5 ml 2.5% sodium hypochlorite for 2 minutes. Then, an LED with curcumin with a concentration of 100 µg for 120 seconds is used.
Intervention group 5: Channels are filled with normal saline and the LED is activated for 120 seconds

Sponsors

Vice chancellor for research,Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Maxillary single-root and human mandibular teeth that have been removed due to periosteum and Decay; Exclusion criteria: Not evolved root; Decay root or previous endodontic treatment; crack and curve more than 30 degrees;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Three sensor sensing power. Timepoint: From the beginning to the end of the treatment. Method of measurement: CFU changes.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mohammad Asnaashary

Laser Application Research Center in Medical Science

laser.cntr@yahoo.com+98 21 2274 9221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026