Comparison of the Effect of Omeprazole,Pantoprazole,Esomeprazole and Lansoprazole on the Patients with Gastroesophageal Reflux Disease

Comparison of The effect of Omeprazole,Pantoprazole,Esomeprazole and Lansoprazole on the Symptoms in Patients with Gastroesophageal Reflux Disease

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171007036616N1

Enrollment

120

Registered

2018-10-01

Start date

2018-01-21

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastro-oesophageal Reflux Disease. Gastro-esophageal reflux disease

Interventions

Intervention 1: omeprazole 40mg daily(the pateint will consume two 20mg omeperazole capsules on fasting every morning for 8 weeks). Intervention 2: Pantoprazole 40mg daily(the pateint will consume one

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Gastroesophageal Reflux Disease with frequent symptoms(2 or more symptoms per week)

Exclusion criteria

Exclusion criteria: Weight Loss History of cancer Odinophagia Dysphagia

Design outcomes

Primary

Measure	Time frame
Heart Burn. Timepoint: 0 , 2 , 4 , 8 weeks. Method of measurement: questionnaire.;Acid Regurgitation. Timepoint: 0 , 2 , 4 , 8 weeks. Method of measurement: questionnaire.	—

Secondary

Measure	Time frame
Total Satisfaction. Timepoint: 0,2,4,8 week. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNima Arezoomandi

Esfahan University of Medical Sciences

qoghnus@gmail.com+98 316532021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026