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Effectiveness of saffron and herbal formula on respiratory symptoms

Effectiveness of saffron and herbal formula (based on chamomile) on respiratory symptoms and inflammatory biomarkers of pulmonary chemical veterans in comparison to placebo

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171007036614N4
Enrollment
160
Registered
2023-10-17
Start date
2023-11-22
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unspecified injury of lung. Unspecified injury of lung

Interventions

Intervention 1: Intervention group, strata 1: Herbal product formulation (containing chamomile, thyme, licorice, jujube, fig, nettle, mistletoe and hyssop) based on the basic study of Karimi et al. (E

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: Confirmation of mustard gas induced lung injury by a pulmonologist Previous asthma Seasonal Allergy Acute respiratory infection Smoking Alcohol consuming

Exclusion criteria

Exclusion criteria: Uncontrolled hypertension Unwilling to participate

Design outcomes

Primary

MeasureTime frame
Dyspnea severity. Timepoint: Before treatment and after 4 and 8 weeks. Method of measurement: St George's Respiratory Questionnaire.;Cough severity. Timepoint: Before treatment and after 4 and 8 weeks. Method of measurement: St George's Respiratory Questionnaire.

Secondary

MeasureTime frame
Interleukin 6. Timepoint: Before treatment and 8 weeks. Method of measurement: ELISA.;Glutathione (GSH). Timepoint: Before treatment and 8 weeks. Method of measurement: ELISA.;Malondialdehyde (MDA). Timepoint: Before treatment and 8 weeks. Method of measurement: ELISA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sadegh Adel Mehraban

Bagheiat-allah University of Medical Sciences

sadeghadel@gmail.com+98 21 8897 4535

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026