Effect of vitamin D3 and calcium on blood lipid

Comparison of combination therapy with vitamin D, calcium and statin with statin alone in reducing blood cholesterol in patients with hypercholesterolemia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171007036613N1

Enrollment

Registered

2018-01-03

Start date

2016-12-10

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypercholesterolemia. Pure hypercholesterolaemia

Interventions

At first, all patients were treated by Atorvastatin 20 mg once daily for six weeks. The second intervention in all patients was adding vitamin D3, 400 IU/day and calcium, 1gr/day (CalTrex capsule once

Treatment - Drugs

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: LDL above 160 mg/dl without or with one of cardiovascular risk factors. LDL above 130 mg/dl with two or more cardiovascular risk factors. LDL above 100 mg/dl in diabetics and patients with history of CVD. Total cholesterol above 240.

Exclusion criteria

Exclusion criteria: Triglyceride above 400 mg/dl. Taking Lipid-lowering agent within one month before recruitment. Supplementary calcium and vitamin D in last 6 months.

Design outcomes

Primary

Measure	Time frame
Triglyceride. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.;HDL. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.;Total cholestrol. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.;LDL. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.	—

Measure

Time frame

Triglyceride. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.;HDL. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.;Total cholestrol. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.;LDL. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Lab test.

—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Sphygmomanometer.;Body mass index. Timepoint: Before intervention, 6 weeks after first intervention and 6 weeks after second intervention. Method of measurement: Standing scale for weight and tape for height.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Sanjari Moghaddam

Aja University of Medical Sciences

alisanjarimoghaddam@yahoo.com+98 218802835055

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026