Comparison of the effect of Acetaminophen, Pethidine and Ibuprofen on pain relief in patients with acute cholecystitis

Comparison of the effect of Acetaminophen, Pethidine and Ibuprofen on pain relief in patients with acute cholecystitis: a triple blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201710059014N191

Enrollment

Registered

2017-10-05

Start date

2017-10-23

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute cholecystitis. Acute cholecystitis

Interventions

Intervention 1: Intervention group 1: Intravenous infusion of 10 mg/kg Acetaminophen in 100 ml normal saline within 30 minutes single dose. Intervention 2: Intervention group 2: Intravenous infusion o

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 75 years; Acute cholecystitis

Exclusion criteria

Exclusion criteria: Pregnancy; using analgesic within pass 6 hours; Addiction to narcotic or psychedelic; Contraindication of Acetaminophen, Pethidine, or Ibuprofen; Chronic renal failure

Design outcomes

Primary

Measure	Time frame
Measuring severity of pain. Timepoint: before infusion and 30, 60, and 90 minutes after infusion. Method of measurement: using Visual Analog Scale (VAS).	—

Secondary

Measure	Time frame
Assessing nausea and vomiting. Timepoint: before infusion and 30, 60, and 90 minutes after infusion. Method of measurement: by taking history.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Rasool Salimi

Besat Hospital

rasoulsl@yahoo.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026