Condition 1: Pain. Condition 2: Anxiety. Pain, unspecified Generalized anxiety disorder
Conditions
Interventions
Intervention 1: Oral gabapentin is given at a dose of 600 mg two hours before surgery. Intervention 2: Oral melatonin is given at 6 mg 2 hours before surgery. Intervention 3: Distilled water is used a
Prevention
Placebo
Oral gabapentin is given at a dose of 600 mg two hours before surgery
Oral melatonin is given at 6 mg 2 hours before surgery
Distilled water is used at a rate of 5 ml 2 hours before surgery
Sponsors
Ahvaz Jundishapor University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion area: Aged 18 and under 60 years old; ASA class ? and ??; Spine surgery; Written permission of study entrance Exclusion area: Emergency surgery; tumor surgery; melatonin or gabapentin allergy; BMI higher than 35; pregnancy or breastfeeding; opioid abuse
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: 2 h before until 24 h after opetration. Method of measurement: Visual Analogue Scale, questionnaire.;Anxiety. Timepoint: 2 h before until 24 h after opetration. Method of measurement: Visual Analogue Scale, questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: 2 h before until 24 h after operation. Method of measurement: sphygmomanometer.;Heart rate. Timepoint: 2 h before until 24 h after operation. Method of measurement: Stetoscope. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Javaherforoshzadeh
Ahvaz Jundishapor University of Medical Sciences
Outcome results
None listed