Rhinoplasty surgical operation. Other plastic surgery for unacceptable cosmetic appearance
Conditions
Interventions
Intervention 1: Magnesium sulphate (50%) with dose of 40 mg/kg administered in 10 minutes before anesthesia induction and continued with 10-15 mg/kg/hr during the anesthesia. Intervention 2: Dexmedeto
Treatment - Drugs
Magnesium sulphate (50%) with dose of 40 mg/kg administered in 10 minutes before anesthesia induction and continued with 10-15 mg/kg/hr during the anesthesia.
Dexmedetomidine with bolus dose of 0.1 µg/kg dissolved in 50 milliliters of normal saline and injected 10 minutes before anesthesia induction and continued with infusion of 0.4-0.6 µg/kg/hr during ane
Sponsors
Vice-chancellor for Research, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: candidate for rhinoplasty operation; minimum 18 and maximum 50 years of age; ASA grade I; informed consent Exclusion criteria: revision rhinoplasty; known allergy to drugs being tested; drug abuse; coagulation disorders
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of surgical field in terms of bleeding and visibility by surgeon of the operation field. Timepoint: during operation. Method of measurement: Fromme and colleagues 6-point grading system.;Surgeon's satisfaction score. Timepoint: At the end of the operation. Method of measurement: 4-point surgeons satisfaction grading system.;Post-operative recovery rate. Timepoint: After recovery. Method of measurement: Modified Aldrete’s Scoring System (duration of the time required to achieve score 9). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Soudabeh Djalali
Iran University of Medical Sciences
Outcome results
None listed