Atrophy of the vagina. Postmenopausal atrophic vaginitis
Conditions
Interventions
Intervention group: The intervention group uses fractional carbon dioxide laser, which is used in 3 sessions and 4 weeks apart..
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: one or more symptoms of VVA (e.g., vaginal discharge, itching, dyspareunia, dryness and urge urinary incontinence). no menstruation for = 12 months. not using local or systemic estrogen therapy. wishing to be sexual active.
Exclusion criteria
Exclusion criteria: : use of hormone replacement therapy (systemic or local) up to 6 month before entry to the study. pelvic organ prolapse stage > 2 (according to POP-Q system). active genital infections. acute or recurrent urinary tract infection. use of any vaginal lubricants. moisturizers or local preparations within 30 days before entry to the study. psychiatric disorders which could interfere with informed consent. any chronic disease that could interfere with study compliance. abnormal uterine bleeding which has no exact diagnosis. malignancies of urogenital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of women who have vaginal dryness. Timepoint: The time intervals for assessing the vaginal dryness before the start of the laser and then one month two months and three months and one year after the laser is done. Method of measurement: questionnaire.;Percentage of women who have urinary incontinence. Timepoint: The time intervals for assessing the vaginal dryness before the start of the laser and then one month two months and three months and one year after the laser is done. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dysuria together. Timepoint: The time intervals for assessing the vaginal dryness before the start of the laser and then one month two months and three months and one year after the laser is done. Method of measurement: questionnaire.;Vaginal itching accompanied. Timepoint: The time intervals for assessing the vaginal dryness before the start of the laser and then one month two months and three months and one year after the laser is done. Method of measurement: questionnaire.;Vaginal discharge accompanied. Timepoint: The time intervals for assessing the vaginal dryness before the start of the laser and then one month two months and three months and one year after the laser is done. Method of measurement: questionnaire.;Dyspareunia. Timepoint: The time intervals for assessing the vaginal dryness before the start of the laser and then one month two months and three months and one year after the laser is done. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Safa Al-Asiri
Tehran University of Medical Sciences
Outcome results
None listed