Comparison of the therapeutic effects of intratympanic injections of Triamcinolon and Dexametasone who suffer from sudden sensorineural hearing loss

Comparison of the therapeutic effects of intratympanic injections of Triamcinolon and Dexametason who suffer from sudden sensorineural hearing loss

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171004036554N4

Enrollment

Registered

2021-12-18

Start date

2022-01-05

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sudden sensorineural hearing loss. Sudden idiopathic hearing loss, bilateral

Interventions

Intervention 1: Intervention group: In the intervention group, using Triamcinolone ampoule 0.4-0.6 cc for Intratympanic injection that performed 6 injections twice aweek. Intervention 2: Control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with SSNH diagnosis who are candidates for intratympanic injection Patients who have a contraindication to receive systemic corticosteroids, such as underlying diseases like diabetes or defective immune disorders . Patients who are interested in receiving intra tympanic corticosteroids instead of systemic corticosteroids .

Exclusion criteria

Exclusion criteria: Patients who are candidates for receive systemic corticosteroids Patients who are not volunteer to receive intratympanic corticosteroids

Design outcomes

Primary

Measure	Time frame
Hearing improvement based on audiometry. Timepoint: Complete response to treatment refers to an increase of 30 dB after 15 to 45 days after IT injection of dexamethasone and triamcinolone. The relative response to treatment refers to an increase of 10 dB 15 to 45 days after IT injection of dexamethasone. An improvement of less than 10 decibels will be considered as no response or failure of treatment. Method of measurement: Based on audiometry.	—

Measure

Time frame

Hearing improvement based on audiometry. Timepoint: Complete response to treatment refers to an increase of 30 dB after 15 to 45 days after IT injection of dexamethasone and triamcinolone. The relative response to treatment refers to an increase of 10 dB 15 to 45 days after IT injection of dexamethasone. An improvement of less than 10 decibels will be considered as no response or failure of treatment. Method of measurement: Based on audiometry.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaleh Habibi

Tehran University of Medical Sciences

s.habibi@Gmail.com0098 21 61190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026