Comparison study of effectiveness treatments on decreasing of craving of stimulant substance user.

Comparison study of effectiveness of Matrix model,repetitive Transcranial Magnetic Stimulation and cognitive rehabilitation on decreasing of craving and assessment of dopamine receptors expression in peripheral blood lymphocytes of stimulant substance user.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171004036553N2

Enrollment

Registered

2018-04-13

Start date

2017-12-22

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stimulant Addiction. Other stimulant related disorders

Interventions

Intervention 1: "Intervention group 1: Outpatient psychotherapy method". In this intervention, the outpatient treatment method is used using a booklet therapy and cognitive behavioral assignments. The

Eligibility

Sex/Gender

Male

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Sex: Male Diagnosis of Substance use of the subjects Having Satisfication of doing project

Exclusion criteria

Exclusion criteria: Using Methadon and the other drugs Patients treated with alternative therapies other than methadone. Patients with severe psychiatric disorders such as psychosis, bipolar depression.

Design outcomes

Primary

Measure	Time frame
Crayving. Timepoint: Before the intervention after the end of the therapeutic interventions and 3 months later. Method of measurement: Questionnaires and cognitive tests.;Gene expression of dopamine receptors. Timepoint: Before the intervention after the end of the treatment interventions. Method of measurement: The real time pcr method.	—

Secondary

Measure	Time frame
Anxiety Score. Timepoint: Before and after the intervention. Method of measurement: Anxiety Questionnaire.;Depression Score. Timepoint: Before and after the intervention. Method of measurement: Depression Questionnaire.;General Welbeing Score. Timepoint: Before and after the intervention. Method of measurement: General Welbeing Questionnaire.;Score of Crayving Assessment. Timepoint: Before and after the intervention. Method of measurement: Craving Assessment Questionnaire.;Screening Score and Addiction Severity Score. Timepoint: Before and after the intervention. Method of measurement: Screening and Measuring the Severity of Addiction.;Work Memory Score and Attention Detection. Timepoint: Before and after the intervention. Method of measurement: Work Memory and Detection Attention.	—

Measure

Time frame

Anxiety Score. Timepoint: Before and after the intervention. Method of measurement: Anxiety Questionnaire.;Depression Score. Timepoint: Before and after the intervention. Method of measurement: Depression Questionnaire.;General Welbeing Score. Timepoint: Before and after the intervention. Method of measurement: General Welbeing Questionnaire.;Score of Crayving Assessment. Timepoint: Before and after the intervention. Method of measurement: Craving Assessment Questionnaire.;Screening Score and Addiction Severity Score. Timepoint: Before and after the intervention. Method of measurement: Screening and Measuring the Severity of Addiction.;Work Memory Score and Attention Detection. Timepoint: Before and after the intervention. Method of measurement: Work Memory and Detection Attention.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Esmaeili

Zanjan University of Medical Sciences

saharesmaeili87@yahoo.com+98 24 3342 0651

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026