The effect of vitamin D supplements on the treatment of diabetes

The effect of vitamin D injection on Endothelial Biomarkers, hs-CRP and blood pressure in vitamin D deficient patients with Type 2 Diabeties

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171003036539N2

Enrollment

Registered

2019-09-15

Start date

2019-02-20

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type II diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: injection of Vitamin D 400000 IU first and one month after the start of the study each time 200,000 IU Duration of study 2 months. Intervention 2: Control group: The control group does

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Diabetes mellitus patients and HbA1c hemoglobin less than 9 levels of hydroxyvitamin D (25 OHD) less than 20 ng / ml Age range 30-60 years

Exclusion criteria

Exclusion criteria: Use of vitamin D supplementation over the past 3 months- Kidney,liver disease,Malabsorption syndrome,Severe infection Pregnancy and lactation Use of insulin

Design outcomes

Primary

Measure	Time frame
P-selectin of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.	—

Secondary

Measure	Time frame
High-sensitivity C-reactive protein (hs-CRP) of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.;Vitamin D of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.;Systolic blood pressure. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Mercury barometer.;Diastolic blood pressure. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Mercury barometer.;Wight. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: scales.;Serum Calcium. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.;Serum Phosphorus. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.;Intercellular Adhesion Molecule-1 of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.;Evalution of patients diet. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Three-day food record.;Beck Depression score. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Beck Depression Inventory2 score.;Serum fasting blood sugar(FBS). Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.;Serum triglyceride level (TG). Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.	—

Measure

Time frame

High-sensitivity C-reactive protein (hs-CRP) of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.;Vitamin D of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.;Systolic blood pressure. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Mercury barometer.;Diastolic blood pressure. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Mercury barometer.;Wight. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: scales.;Serum Calcium. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.;Serum Phosphorus. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.;Intercellular Adhesion Molecule-1 of serum. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: ELISA method.;Evalution of patients diet. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Three-day food record.;Beck Depression score. Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Beck Depression Inventory2 score.;Serum fasting blood sugar(FBS). Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.;Serum triglyceride level (TG). Timepoint: Before the intervention and two months after the start of the study. Method of measurement: Enzymatic method.

—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactfarhang Mirzavandi

Yazd University of Medical Sciences

f.mirzavandi@ssu.ac.ir+98 353538209143

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026